The genus Crocidura is one of the largest genera among mammals and widely distributed in Eurasia, Africa, and Southeast Asia. We review the recent advances in taxonomic and phylogenetic studies of this genus in East and Southeast Asia. Sympatric distributions of two or more species are known in several localities. Karyotypes of East and Southeast Asian species are divided into several groups. From karyological comparison and molecular phylogeny, those groups are suggested to have formed by geographical isolation in islands and in the continent in East and Southeast Asia. To clarify evolutionary history of East and Southeast Asian species, comprehensive studies with the West Asian and European species from karyological and molecular approaches are desired.